Huperzine A inhibits immediate addictive behavior but not behavioral sensitization following repeated morphine administration in rats
نویسندگان
چکیده
منابع مشابه
Ascorbic acid inhibits nicotine-induced behavioral sensitization in male mice
Repeated administration of nicotine causes incentive and behavioral sensitization in animals. Ascorbic acid administration inhibits some effects of nicotine. In the present study, the effect of ascorbic acid administration on nicotine-induced behavioral sensitization in Male Swiss-Webster mice (20-25 g) was investigated. Animals were injected with nicotine (0.25 mg/kg, i.p.) once daily for seve...
متن کاملAscorbic acid inhibits nicotine-induced behavioral sensitization in male mice
Repeated administration of nicotine causes incentive and behavioral sensitization in animals. Ascorbic acid administration inhibits some effects of nicotine. In the present study, the effect of ascorbic acid administration on nicotine-induced behavioral sensitization in Male Swiss-Webster mice (20-25 g) was investigated. Animals were injected with nicotine (0.25 mg/kg, i.p.) once daily for seve...
متن کاملEffect of repeated morphine and tramadol administration on the motor behavior in the neonatal period
Introduction: Motor behavior and coordination impairment are known side effects of opioid treatment, yet very few studies have investigated the effects of tramadol on motor behavior, or compared its effect with the effect of an opioid. This study investigates the effects of chronic injection of morphine and tramadol on rat motor function during infancy. Methods: Neonate rats (n=56) were rand...
متن کاملEffects of a single and repeated morphine treatment on conditioned and unconditioned behavioral sensitization in Crayfish.
Recent neuroethological work suggests that drug-sensitive reward in Crayfish represents a useful new model system for the study of drug dependence. Monoamine re-uptake mechanisms, which are conserved across vertebrate and invertebrate taxa, offer sites of action for testing drug-induced behavioral sensitization. The present study explored drug-associated behavioral sensitization in Crayfish by ...
متن کاملIntrathecal administration of epinephrine inhibits and reverses analgesic tolerance to analgesic effect of morphine in rats
Introduction: Several researches have reported that stress is able to inhibit the development of morphine tolerance via activating of Hypothalamic-Pituitary-Adrenal (HPA) axis. In the present study we tried to examine the effect of epinephrine, the product of adrenal medulla, on the development of morphine tolerance. Methods: Analgesic tolerance was induced by intrathecal (i.t.) injection of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2017
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2017.4097